I think it should be
4x+10+-22
My reasoning is
4 times a number increased by 10 is -22
4 times a number would be 4x. We don't know what the number is so it would be x in this. 4x INCREASED would be +. 4x+10. All that is left is -22, it is next to "is" which would be our equals sign.
4x+10=-22
